Thursday 17 May 2012

GPAT Question - 1 to 20

1. The process refers to whereby tissue callus or cells may be induced to form shooths,
roots and complete plants
a) Somatic hybridization b) Embryogenesis c) Organogenesis d) none of these
2. a patient takes an triple antibiotic ointement ( eg- neosporin) & suffer from contact dermatitis.....which cmponent cause this...? 
1 neomycin
2 bacitracin
3 polymyxin b
4kanamicin
3. Scopolamine on hydrolysis with barium hydrochloride gives:
a) Tropanol and tropic acid b) Scopine and tropic acid c) Ecgonine and benzoic
acid d) Benzyl ecgonine and methanol
4. Mixture of equal parts of chromic acid & nitric acid is used for
a) staining cellulose walls blue b) removal of fixed oils & fats c) staining lignified
walls pink or red d) disintegration of scelerenchymatous tissue
5. Morphine is treated with –CH3I in aqueous KOH gives (-) codeine, which is not
soluble in alkali; codeine can be oxidized with chromic acid to acid to codeinone.
Which group is responsible for oxidation?
a) Primary –OH b) Phenolic –OH c) Secondary –OH d) Tertiary –OH
6. Antibodies and antigens can attach to solid-phase supports and still maintain their
full immunological capabilities is principle in which diagnost test?
a) Shick test b) Widal test c) SGPT test d) ELISA
7. A proteolytic enzyme obtained from cultures of Bacillus subtilis used to dissolve
necrotic tissue in burns, bed sores & ulcerated wounds
a) Sutilains b) Urokinase c) Alteplase d) Bromelain
8. Succulent growth from helium covering the entire seeds is characteristic of
a) Colchicum b) Cardamom c) Nutmeg d) Castor
9. Capillary columns have an internal diameter of 1mm or less and are used in gas
Chromatography and are constructed of
a) Fused silica(very high purity glass) b) Diatomaceous earth
c) Calcium carbonate d) China clay
10. When an atom is excited by removal of an electron from inner energy level, it may
return to its normal state by transfffering an electron from some outer level to the
vacant level. The energy of this transition appears as
a) α-rays b) β-rays c) γ-rays d) X-rays
11. In polarography half wave potential is point where
a) i = id b) i = 2id c) i = id/2 d) i = id/4
12. Succulent growth from helium covering the entire seeds is characteristic of
a) Colchicum b) Cardamom c) Nutmeg d) Castor
13. Which of the following is not an
aminoglycoside antibiotic?
a)Tobramycin
b)Lincomycin
c)Neomycin
d)Sisomycin
14. kreis test is used for the identification of-
a)ester value
b)peroxide value
c)rancidity value
d)reichert value
15. whch is highly perfused organ
a.heart
b.lungs
c.kidney
d.brain
16. rose bengal medium is for?
a. virus .
b. bacteria.
c.fungi.
d. none
17. Wider phloem fibres, larger- starch grains, longer fibres and abundant cork are
Charachateristic of
a) Cinchona succiubra b) Cinnamomum zeyanicum c) Cinnamomum cassia
d) Hoarrhena antidysentrica
18. Bentonite is
A) o/w b) w/o c) o/w/o d) both a & b
19. Palthe senna is identified with
a) Absence of anthraquinone glycoside b) Lamina is denser
c) Presence of anthraquinone glycoside d) with tapering apex
20. kreis test is used for the identification of-
a)ester value
b)peroxide value
c)rancidity value
d)reichert value

Here are some tips for last month study 
1. Don’t try to read any thing new. Focus on revision.
2. Try to finish GPAT: A companion as soon as possible
3. Cognosy : Read only B.S, C. constituent, Test, Microscopy of imp drugs, uses and adulterants (kokate is sufficient)
4. Cology: Classification, MOA, special Adverse effect, uses 
5. Med.chem: Only structure 
6. Ceutics: All tables and specification from lachman’
7. Don’t time pass with IPL 
8. Revision, Revision, Revision, Revision, Revision, Revision, Revision,…..:D :D :D 
9. AND FINALLY KEEP CONFIDENCE YOU CAN DO IT.

Urine Color Changes

Orange-
Rifampcin,Phenozopyridine,Doxorubicin,Warfarin

Blue-Amitryptalline,Indomethacin

Red/Brown-Food Dyes

Pink-Beet Root

Golden Yellow-Excess of laxatives

Neon Yellow- Excess of vitamin supplements
Poison act- 1919
Pharmacy act- 1948
Cruelty to animal act- 1960
DPCO- 1987
D & C Act- 1940
Magic Remedies- 1955
MTP Act – 1971
Insecticide act- 1968
Dangerous Drug Act- 1930
National Pharmaceutical Pricing Policy- 1997
Adultrant
1-Buchu- Barsoma Cermulata
2-Pale Catechu- Acacia Catechu
3-Tragacanth- Sterculia Urens
4-Saffron- Corn silk
5-Digitalis- Verbascum Thaspus
6-Liquorice- Arbus Preecatorious
7-Cardamom- Orange seeds
8-Areca Nut- Sago palm nuts
Mechanism of action
1-DNA Dependent RNA Polymerase- Rifampcin
2- RNA Dependent DNA Polymerase-
Zidovudine
3-Proetin Synthesis Blocker-
Erythromycin ,Chloramphenicol & Tetracycline
4-ACE Inhibitor- Captopril
5-Ca Channel Blocker- Nifedipine,Diltiazem
6-COX Inhibitor- Asprin
7-GABA Facilitator- Benzodiazepines
8-Antimetabolites- Methotrexate
9-Loop Diuretics- Frusemide
10-High Ceiling Diuretics- Spironolactone
11-Alteration of bacterial DNA- Choloroquine
12-Inhibition of Viral replication-
Amantidine,Acyclovir
13-H1 blocking agent- Mepyramine,Loratadine
14-H2 Blocking agent-
Rantidine,Cimetidine,Famotidine,Cyprohaptidine
15-Proton Pump inhibitor- Omeprazole
16-DNA Metabolism Inhibitors- Quinacrine
(Mepacrine)
17-Spindle Poison- Vinca,Griesofulvin
18-Folic acid synthesis inhibitor- DDS
19-GABA Inhibitor- Sodium Valproate
20-DNA Synthesis Prevention – Nalidixic Acid
21-Prostaglandin Synthesis Inhibition-
Oxyphenbutazone,Ibuprofen
22-Mycolic acid synthesis inhibition- INH
23-Folic acid antagonist- MTX,PAS,DDS &
Primethamine
24-Desruption of DNA structure- MNZ
25-Inhibition of cell wall synthesis- Beta
lactam antibiotics(penicillin)
26-Release of nor epinephrine- Ephedrine
27-Ergosterol Biosnythesis Inhibitors-
Clotrimazole,Miconalzole,Ketoconazole
28-Ach esterase inhibitors-
Physostigmine,Neostigmine,Edrophonium,Metrifonate
29-Reverse Transcriptase Inhibitors-
Stavudine,zidovudine
30-Inhibition of HIV Protease- Amepranavir
31-DNA Gyrase Inhibitor- Cinoxacin
32-Inhibition of DNA Polymerase-Gossypol
33-NMDA Receptor Antagonist-
Amantadine ,Ketamine,Dextromethorphan,Memantine
& Nitrous Oxide
34-DNA intercalating agent-
Daunorubicin ,Doxorubicin,Ellipticin &
Ethidium Bromide
35-Antim mitotic agent- Amphethenile
36-Alkylating agent- Thiotepa
37-Alpha receptor antagonist- Phentolamine
38-Beta receptor antagonist-
Propanolol,Aplrenolol
39-Alpha receptor agonist-Norepinehrine
40- Beta receptor agonist- Isoproterenol &
Salbutamol
41-DNA Adduct Formation- Procarbazine
42-Carbonic anhydrase inhibitor-
Acetazolamide
43-Phosphodiestrase Inhibitor- Theophylline
44-Thrombin action prevention- Heparin
45-Xanthine oxidase inhibitor- Allopurinol
46-Cholinergic Blockade- Ipratropium
47-Adenosine Deaminase inhibitor-
Crisnatapase
48-Immunomodulation- Imiquimod
49-Amino acid transfer interference-
Econazole
50-Mast Cell Stabilization- Ketosifen

1.Deadly Night Shade- Atropa Belladona
2.Bavchi- Psoralea
3.Calabar Bean- Physostigma
4-Fox Glove- Digitalis
5-Indian Tobbaco-
6-Rattle Snake-Senega
7-Ghritkumari/Kumari- Aloe vera
8-BitterApple-Colcynth
9-Kalmegh-Andrographis
10-Vidang-Gurmar
11-Flaxseed- Linseed
12-Devil's dung-Asafoetida
13-American Podophyllum- May apple
14-Scammony root- Ipomea
15-Wild Saffron-Colchicum
16-Our Lady's Thistle-Catharanthus
17-Salad Oil-OliveOil
18-Panama Wood- Quillaria Bark
19-Chinese Cassia- Cinnamon
20-Japanese Isinglass- Agar
21-Bishop's Flower- Visnaga
22-Black Mustard- Brassica Nigra
23-American Wormseeed-Chenopodium
24-Wild Yam-Dioscorea
25-Spanish fly-Cantahrides
26-Teel Oil- Sesame Oil
27-Grains of Paradise-Guinea Pepper
28-Rosin-Colophony
29-Chaulmoogra-Hydnocarpus
30-Cyamposis- Guarmgum
31-Hogweed-Punarnawa
32-Sacred Basil-Tulsi
33-Caltrops Fruit-Gokhru
34-Anticancer Plant-Campotheca
35-Spurred Eye-ergot
36-Indian Oleander-Kaner
37-Medagascar Periwinkle-Vinca
38-Anant Mul- Tylophora
39-Okozerite-Shilajit
40-Indian Kino Tree- Pterocarpus
41-White Lead Wort-Chitrak
42-Rasna-Galanga
43-Yellow Oleander-Thevetia
44-Indian Pennywort- Brahmi
45-Febrifuge Plant-Kantkari
46-Bengal Quince-Bael
48-Indian Gooseberry-Amla
49-Pricky Chaff Flower-
50-Love in mist- Kalijiri

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