Thursday 17 May 2012

classifiacation of anti-cancer agents


classifiacation of anti-cancer agents


CLASSIFICATION OF ANTI – CANCER AGENTS:
 1.      ALKYLATING AGENTS:
1. NITROGEN MUSTARDS :  mechlorethanine
                                         Cyclophosphamide
                                         Ifosphamide
                                         Mephalan  
                                         Chlorambucil

 2.ETHYLENEIMINES AND METHYLMELANINE :   altretamine
                                                                            Thiotepa

 3.METHYL HYFRAZINE DERIVATIVE : procarbazine

4. ALKYL SULFONATE: busulfan

5. NITROSOUREAS : carmustine
                                  Lomustine
                                  Streptozocin : used in treatment of maligmnent pancreatic insulinoma

6.TRIAZENES:     dacarbazine : (DTIC)
                            Temozolomide.

 7. PLATINUM CO-ORDINATION COMPLEXES: cis platin
                                                                          Carboplatin
                                                                          Oxalipaltin

 2.      NATURAL PRODUCTS:
    1. VINCA ALKALOIDS : vinblastine
                                                         Vincristine
                                                         Vinorelbine

                  2.TAXANES : paclitaxel
                                        Docetaxel

                  3.EDIPODOPHYLLOTOXINS: etoposide
                                                                Teniposide

                   4.CAMPOTHECINS : topotecan
                                                    Irinotecan


3.ANTIBIOTICS:  dactinomycin (actinomycin –D)
                               Daunorubicin  (daunomycin)
                               Doxorubicin

 4. ANTHRACENEDIONE DERIVATIVES: mitoxantrone
                                                                     Bleomycin
                                                                     Mitomycin
 5.ENZYMES: L- asparaginase.

 6. MONOCLONAL ANTIBODIES: bevacizumab
                                                        Cetuximab
                                                        Rituximab
                                                        Transtuzumab

 7.      ANTI – METABOLITES:
    1.   FOLIC ACIDS ANALOGS : methotrexate
                                                                   Pemetrexed.

                  2.PYRIMIDINE ANALOGS: 5 – flurouracil
                                                                 Capecitabine
                                                                 Cytarabine
                                                                 Gemcitabine

                 3.PURINE ANALOGS AND RELATED INHIBITORS: 6 – mercaptopurine
                                                                                                Pentostatin
                                                                                                  Cladribine
                                                                                                 Hudarobine.

8.      HORMONES AND ANTAGONISTS :
           ADRENOCORTICAL SUPPRESSANATS : mitotane
                                                                         Aminoglutethimide

          ADRENO CORTICOSTEROIDS : prednisone

          PROGESTINS: hydroxyl progesterone caproate
                                  Medroxy progesterone acetate
                                  Megestral acetate.

         ESTROGENS: diethyl stilbesterol
                               Ethinyl estradiol

        ANTI – ESTROGENS: tamoxifen
                                          Toremifene

        AROMATASE INHIBITORS : anastrazole
                                                     Letrozole
                                                     Exemestane.

        ANDROGENS : testosterone propionate
                                Fluoxymesterone

         ANTI – ANDROGEN : flutamide
                                           Cyprotrone

         GONADOTROPIN- releasing hormone analog : leuprolide.


 9.      MISCELLANEOUS AGENTS:
            SUBSITUITED UREA : hydroxyl urea

            DIFFERENCIAL AGENTS : tretinoin
                                                     Arsenic
                                                      Trioxide

           PROTEIN TYROSINE KINASE INHIBITOR: imatinib
                                                                             Gefitnib
                                                                              Erlotinib.

          PROTEASOME INHIBITOR : bortezomib

          BIOLOGICAL RESPONSE MODIFIERS : interferon alpha
                                                                        Interleukin 2
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2 comments:

  1. ITS BETTER TO WEAR-OUT THAN TO RUST-OUT!!!!!!24 July 2012 at 04:05

    good job!! These are really very helpful!! :)

    ReplyDelete
  2. GERTRUDIS CANDELARIO16 June 2019 at 07:17

    I have long felt a special connection with herbal medicine. First, it's natural, Charlie attended the same small college in Southern California - Claremont Men's College - although he dropped out of school to enroll in the Julliard School of Performing Arts in New York. York. Had he been to Claremont, he would have been senior the year I started there; I often thought that was the reason he was gone when he discovered that I had herpes. So, my life was lonely, all day, I could not stand the pain of the outbreak, and then Tasha introduced me to Dr. Itua who uses her herbal medicines to cure her two weeks of consumption. I place an order for him and he hands it to my post office, then I pick it up and use it for two weeks. All my wound is completely healed no more epidemic. I tell you honestly that this man is a great man, I trust him Herbal medicine so much that I share this to show my gratitude and also to let sick people know that there is hope with Dr. Itua. Herbal Phytotherapy.Dr Itua Contact Email.drituaherbalcenter@gmail.com/ info@drituaherbalcenter.com. Whatsapp ... 2348149277967
    He cures.
    Herpes,
    Breast Cancer
    Brain Cancer
    CEREBRAL VASCULAR ACCIDENT.
    Hepatitis,Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis.Alzheimer's disease,
    Dementia.Tach Disease,Shingles,
    Lung Cancer
    H.P.V TYPE 1 TYPE 2 TYPE 3 AND TYPE 4. TYPE 5.
    HIV,Arthritis,Amyotrophic Lateral Scoliosis,Fibromyalgia,Fluoroquinolone Toxicity
    Cervical Cancer
    Colo-rectal Cancer
    Blood Cancer
    SYPHILIS.
    Diabetes
    Liver / Inflammatory kidney
    Epilepsy

    ReplyDelete

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