Sunday 26 February 2012

NIPER JEE 2011



  •  NIPER 2011 PAPER
    Niper 2011 Paper
    1)Plantago…seed,root,bark
    2)Aegle marmelose family…Rutaceae,malvaceae
    3)competitive inhibitor….increase substate level
    4)Short actin Drug….propofol,thiopental
    5)Morphine discovered in…1904,1820
    6)kaolin…hydrated Al silicate,hydrated Mg silicate
    7)Controlled Drug delivery sym which is usd…HPMC,phalate,DCP
    8)morphine…analgesic,anticonvulsant,both,none
    9)Dry heat soln filling…..Dry heat sterilizatn,moist heat,aseptic fillin
    10)D-glyceraldehyde configuration…S,R,RS
    11)D-threose,D-erythrose,Lthreose related ques
    12)erythrose and threose are???......distereoisomers,epimers,Enantiomers
    13)Kaya skin clinic by company…ITC,
    14)Indian institute of homeopathy??...Kolkata,jaipur,Bombay
    15)preterm delivery vch drug use??..Atosiben,sulfoprostone,oxytocin
    16)Psoralia obtaind from..Apigenin,Umbeliferone
    17)Vch of following obtaind frm marine????...pralidoxime,heparin,both,none
    18)Heparin ant..Ans protamine sulphate
    19) 8 hrs…40km/hr…60 km/hr….ans 400
    20)S is taller than a,a is taller than b lyk ques
    21)witting reaction…phosprous
    22)Cardinolide…butanone,batanedione,butanolides
    23)Propranolol chemical name
    24)Ehrlich reagent…P-dimethyl benzaldehyde
    25)BCE;FGI:…
    26)i-methyl benzoate..ii..phenyl acetate,,iii Acetophenone..IR range,,i=ii>iii,i>ii>iii
    27)NH gives peak at..780,1100,3400
    28)Stat phase nd mobile phase in RP chromatography..
    29)Intracutaneous Max vol….0.01,0.1,0.2,1
    30)BCCI memb
    31)Fecl3+catechol colour….purple,red,green
    32)Third generation sulphonamide usd in diabetis…Repaglinide,Glimipride,metformin,phenformin
    33)Endothelial cell present in..Blood,lung,
    34)Vch tissue has slowest equilibrium drug in blood…brain,fat,muscle,liver
    35)platelets obtained from?? Ans megakaryotes
    36)h2o nd D2O attack…Elimination,SN2,SN1
    37)Walden inversion….SN1,SN2,E1,E2
    38)Blood pH..7.4
    39)Crystalline str related ques…
    40)Vch method best suit to convert amorphous to crystalline….micronization,spray drying,any of above
    41)emulsion measurement not by….electric charge,light scaterin,
    42)DLVO theory…
    43)microemulsion globule size…
    44)beta galactosidase…SDS page…Band…2,1,,,,1,2….11….22…
    45)PCR sequence
    46)vch of following is not diuretic???..triamterine.indapamide,furosemide
    47)Vch f followinnot active??...Allene,biphenyl.meso tartaric,None…
    48)Gossypol…..not chiral,restricted rotation..
    49)Eucalyptos oil ctn…geraneol,1-8 cineole,
    50)AU..Bz..Cy….ans DX
    51)20student height 120,10 student height 100…Avg height ans 105
    52)Sania mirza….
    53)German company take over.teva,sanofi,Pfizer..
    54)book..fatima…
    55)WOF used in tretmnt of diarrohea…erythromycin,domperidone,cisapride nd one new drug
    56)cycloaddition..dial alder reactn
    57)thinamerin dehydrogenation produce….antracene,naphthalene…
    58)synthetic Ach better than natural Ach….due to slwer hydrolysis…
    59)If increase dose f salbutamol,decrease actn by…downregulation,upregulatin…
    60)vch is permeable..polystrene…
    61)bond energy…..
    62)Tymoleptics??
    63)Max absorption from cell memb….ionizdform,unionized form…
    64)WOf is not sede efeect of phenothiazine???
    65)WOFis not hepatotoxic??..rifampicin,isoniazid,ethambuto,streptomycin
    66)Inhibit Aminotranferase nd 30S….tetracycline,macrolide
    67)Inhibitr f 50 s ….macrlide,tetracycline
    68)synonym…Graphics
    69)Pictorial
    70)magnaminous
    71)Rebate
    72)WOF is antituberculosis drug???..Ethambutol..
    73)Relience take over vch air li9ne?
    74)Antinomycin D nd Rifampicin related confusin ques
    76)DNA polymerase havin activity??...5 to 3,3 to 5,5 to 3 wth exonuclease,
    77)SP angle…180
    78)sesqueterpene havin isoprene unit,,,ans 3
    79)In chewable tablet vch is usd?? Mannitol…
    80Manitol used bz..Ans negativ heat f soln
    81)CAP hydrolyze at pH….2.1..3.3…5.4….Ph indepedant
    82)Anandamide….
    83)Condensed tannin…Ans proanthocyanidin
    84)Not sterilized by moist heat…taflon,polystyrene,polyethylene
    85)leucopenia…decrese size of WBC,increase size f WBC
    86)Estrogen higher level vch toxicity produce??...wieght loss,thrombophlebitis…
    87)exothermic reaction Enrgy f product….Less,more
    88)Father f pharmacognosy..hippocrates
    89)benzyme intermediate..
    90)Organic cmpd+UV….electronic transition
    91)Quantitativ estimation by..UV,IR,Mass,Nmr
    92)St phase in cellulose chromatography…silica gel,water without OH.water with OH
    94)PEG liposome….
    95)WOF is wrong…aquacoat means enteric coatin
    96)WOF is nt disacchrides….sucrose,maltose,lactose,glucopyranose
    97)Glycolysis occur in…cytosol,mitochondia,nucleolus,nucleus
    WOF occur in mitochondria..steroid synthesis,fat synthesis,
    98)feed back inhibitin…
    99)composite family nd one source belong to….terpene,alkaloids,glycoside,tannis
    100)IR activity seen…change in dipole moment…
    101)300 Mhz…c13 Nmr???.....75
    102)Increse polarity..n to pi* transitn…bathochromic shift,hypsochromic shift…
    103)WOF increase the QT interval…terfenadine nd other 3 option
    104)WOF is action of diuretic..Urine formation,glucose formation,
    105)Metabolite of hormone stored in…pancreas,adrenal medulla..
    106)Bile is stored in…pancreas,gall blader,
    107)Body Temp controlled by…hypothalamus…
    108)Iregulation in moment due to…..cerebrum,cerebellu,
    109)cardiac output/min calld……..cardiac cycle,cardiac output,force f contraction
    110)most intense peak…Base peak…
    111)Molar extinction coefficient Unit….
    112)Acute amoebic dysentery vch drud used..metronidazole,chloroquine..
    113)Flourouracil..ans inhibit thymidylate synthesis…
    114)Folate deficiency by…methotraxate..
    115)NSAIDS induced GITproblem handled by…mesoprostol
    116)Insulin ph 5..hw to make longer actin insulin lyk dt ques…increase pH,lower pH
    117)Longer actin penicillin…procain penicillin and other qption
    118)WOF used as sorbent in tablet??.....MCC,silica,both,none
    119)Acetylene value……ans lower than alkene
    120)free radical stability….
    121)free radical str…..ans planar
    122)str of twisted boat…..
    123)Tartaric acid inactive bz…..internal plane f symmetry..
    124)WOF is prodrug..sulindac,sulphasalazine,aspirin
    125)WOF is induced in allergy…IgE
    126)WOF is participate in complement sym…IgG,IgM,IgE,IgA
    127)Disinfectant fluid….ans Sch O
    128)Vasaka leaf shape…ans lanceolate
    129)glandular type,,,fracture….
    130)agaropectin made up f….galactose nd uronic acid,glucose nd uronic acid
    131)Arhenious Eqn related ques
    132)Handersn hechalbatch…pH
    133)Inflamation f brain…Ans meningitis…
    134)GABA..increse cl level
    135)Stainin..WOF is true abt gram positive stain
    136)Eculle method 4 ans volatile oil
    137)Vulcanizin agent…..S,SO2
    138)IND full form
    139)WOf is not product f dabur….meswak,glucose D,odomus
    140)Colour added in vch step….syrup coatin
    141)Interfacial tensn measured by..ostwald,brook field
    142)vch is adultrant f saraca indica
    143)tablet strength increser by ques lyk dat…..MCC,lactose
    144)Mg stearate added in vch step of wet granulation…durin granulation,aft granulation
    145)GC principle…adsorption,partition,both
    146)Na salt f sachrin usd as….solublizin agent,bulkin gent,aweetnin agent
    147) IV emulsion isotonic wth,,Nacl,KCL
    148)IP h2O2….20%,80% lyk ques
    149)Arsenic test apparatus use??…nessler cylinder
    150)Doctor without border smthin lyk ques
    151)subsidy definition..
    152)dideoxy nucleotide differ frm deoxy nucleotide by…….less OH at 3rd carbon,More OH at 3rd carbon,lessH at 3rd carbon,more H at 3rd carbon
    153)In m-RNA nucleotides are joinee by…phosphodiester bonds,glycosidic bond,hydrogen bond
    154)Vd=X/C related ques,,ans 5 L
    155)WOF is stron base….dimethyaniline,Pyrole,aniline,Pyridine
    156)Enteric coated takes time in 0.1 N hcl…60,120,180,45
    157)WOF used in efervesent tablet…citric acid+Na bicarbonate.
    158)Wet granulation vch is nt used…Roler compactor,sigma blade mixer.
    159)Contact angle related ques
    160)Draves test,,ans weting angle
    161)Cafeeine gives..ans murexide test
    162)Meyer’s reagent….
    163)Rhem rhizome use…..purgative,carminative,
    164)Meltin f DNa increase..adeneni nd guanine,adenine nd thiamine,cytosine nd thiamine,
    165)Topotecan…natural,synthetic,
    166)H.pyroli induced hyperacidenia treated by???
    167)clonidine….Antihypertensive,
    168)Daughter cells divided in…Prophase,Anaphase,telophase
    169)Company acquire vch hospital???..
    170)Cyanide 540 UV gives colour……Blue,green,Red
    171)PCI constituted by…central govt,state govt…
    172)Carbopol….PVA,PVP
    173)antioxidant wth reducing Prop??...tocopherol,hydroxyurea
    174)Preservative used in ophthalmic??benzal konium Cl
    175)Pharmaceutical Rotation by…molecule,crystal,both,None..
    176)Increase lipase level indicate vch organ functn test…
    177)USP apparatus 2…ans Paddle..
    178)Streptomycin side effect….ans vestibular disturbance
    179)Podophylotoxin…lignan dvt….
    180)str of ketone treated wth LiAlH4

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