Mechanism of Action of drugs

MOA OF SUM IMP DRUGS:

1.Nalidixic Acid-Prevent DNA sysnthesis
2.Dapsone-Folic acid sysntheses inhibitor
3.Vinca alkaloid-Mitotic Spindle formation prevention
4.anthracycline-Intercalation of DNA
5.Methotraxate- Folic acid reductase inhibitor.
6.Warfarin-Vit k antagonist
7.Zidovudine- Inhibits the enzyme reverse tranascriptase ,preventing DNA replication
8.Metronidazole- disruption of helical structure of DNA
9.Tetracycline- Inhibits Protein smyntheses by acting on 30 S unit of ribosome
10.Erythromycin- Inhibits Protein smyntheses by acting on 50 S unit of ribosome
11.Chloroquine- Binds and alters properties of microbial and fungal DNA
12.Diazepam- GABA facilitator
13.Acetazolamide- Carbonic anhydrase inhibitor
14.Allopurinol- Xanthine oxidase inhibitor,inhibitor of uric acid
15.Fluconalzole- P450 enzyme 14a-demethylase Inhibitor
16.Salbutamol-Beta 2 receptor agonist
17.Tolnaftate- Inhibit squalene epoxidase which is necessray for ergosteral syns of fungal cell wall
18.Griesofulvin-inhibits fungal cell wall activity
19.Chloramphenicol-Inhibition of Protein syntheses
20.Levodopa- Replenish Brain deleted dopamine
21.pentylene tetrazole-brainstem stimulant
22.nikethamid-respiratory stimulant
23.strychnine-spinal stimulant